Five school kids in Eltham were taken to hospital with one left in a coma after reportedly using a vape laced with the illegal drug, Spice.
Police officers were called to reports of a number of students feeling unwell at the school on January 29.
Some of the kids suffered symptoms including a reduced level of consciousness, vomiting, and confusion.
It is thought by police that they may have ingested a vape liquid which contained the drug, Spice.
One of five youngsters was placed in an induced coma and was later revived and recovered.
A spokesperson for New Scotland Yard said: “We are aware of illegal drug products being sold in vape form by illegal drug dealers.
"We understand that these vape products may be described to those buying them as containing THC which is a compound found in cannabis.
“In recent weeks, four vapes have been sent for testing and all were found to contain the drug spice rather than THC.
“This included one of the vapes recovered after an incident in Eltham.
“Our message to the public is clear. You should never buy illegal drugs since you simply do not know what these products contain.
“We have been liaising with the Office for Health Improvement and Disparities about this issue.”
Spice is known as the “zombie-drug” because it can leave users in a zombie-like state, according to healthcare experts.
Parents, carers and schools are being alerted to this problem and are requested to seek medical assistance if appropriate.
Police enquiries are underway to establish the full circumstances.
It is unknown which school in Eltham the incident happened at.
The full statement from Metropolitan Police says: “On Monday, 29 January, officers were called to a school in Eltham after a number of students reported feeling unwell.
“Five teenagers were hospitalised. It is thought that they may have ingested the vape liquid.
“One of the teenagers was placed into an induced coma but was later revived and recovered.
“Students have suffered symptoms including a reduced level of consciousness, vomiting and confusion.
“It can take one to three hours before the effects become apparent.
“Parents, carers and schools are being alerted to this problem and are requested to seek medical assistance if appropriate.
“Enquiries are under way to establish the full circumstances.”
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