A 16-year-old boy arrested on suspicion of the murder of a 22-year-old woman was "known to" the victim, police say.
The boy was arrested after officers were called to a home in Spenlow House in Jamaica Road, Bermondsey just after 10pm on Christmas Eve.
Ambulance crews and London's Air Ambulance were also called.
The woman died at the scene and her family have been informed.
The 16-year-old suspect was arrested a short time later.
He remains in custody at a south London police station.
Chief Superintendent Seb Adjei-Addoh, local policing commander for Southwark, said: "This is a tragic incident and my thoughts are with the woman's family and friends at this incredibly difficult time.
"We recognise this will also have an impact on the wider community and we will have additional patrols in the area over the coming days to provide reassurance."
Detectives from the Met's Specialist Crime Command are leading the investigation.
Detective Chief Inspector Brian Howie added: "Our investigation continues and a team of detectives are working at pace to establish what happened that resulted in a young woman losing her life.
"My thoughts, and those of my team, are with her family and friends at this awful time.
"One person has been arrested, however we still need to hear from anyone who was in the Spenlow House area between 19:00hrs and 23:00hrs on Christmas Eve and may have seen or heard anything suspicious.
"I would urge anyone with any information that may be relevant to our investigation, no matter how insignificant it may have seemed at the time, to come forward immediately."
A post-mortem examination will take place on Tuesday, December 26.
Anyone with information about the incident is asked to call 101 quoting CAD 5855/24Dec. Information can also be shared online.
You can also contact the independent charity Crimestoppers anonymously on 0800 555 111.
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